Ivyo bitera umubiri gukura birakoreshwa cane kugira ngo umuntu agire ibiro vyinshi. Ariko rero, gukoresha nabi imiti irwanya indwara birashobora kugira ingaruka mbi nyinshi ku bantu. Gutegura uburyo bundi bwo gusubirira imiti igabanya ubukana bw’indwara ni ikintu gikenewe cane mu bijanye n’ubworozi bw’amatungo. Intumbero y’iyi nyigisho yari iyo kumenya ingaruka z’ivyo kwongera ku ngaburo nk’ibishobora gusubirira imiti irwanya indwara (ASs) ku guhagarika imigera, ku bushobozi bwo gukura, ku miterere y’amaraso n’ubudahangarwa bw’umubiri biciye mu gusesangura (meta-analysis) no ku gusesangura kw’uruja n’uruza (NMA). Ikindi, AS z’intango, z’inyuma n’iz’inyuma zamenyekanye mu kugereranya ivyo vyavuyemwo n’ivyo mu miti irwanya indwara.
Ivyaranguwe
Mu nyigisho 16.309 zamenyekanye, inyigisho 37 z’ingaruka zo guhagarika imigera nk’ivyo kwongera ku ngaburo zaciwe mu ncamake ingurube 89 zashizwe mu meta-analysis na NMA (ingurube 10.228). Twaraciyemwo mu ncamake amashirahamwe 268 y’ingwara 57 n’ubwoko 32 bw’imigera. Ingaruka z’uguhagarika imigera zashizwe mu rutonde rukurikira: amapeptide arwanya imigera (AMPs) ≈ antibiyotike > aside y’ibinyabuzima > ibiva mu bimera > oligosaccharides. Twaragerageje ivyungura 11 vy’ibifungurwa n’ivyavuyemwo 11 kugira ngo tubone ko bifitaniye isano. Ugereranije n’ibifungurwa vy’ishimikiro, ibiva mu bimera, ivyitwa peptides birwanya imigera, ivyitwa probiotiques, ivyitwa trice elements, asides organiques, phages, lysozymes, enzymes na oligosaccharides vyatumye umuntu akura neza cane (P < 0,05); aside z’ibinyabuzima, probiotiques, ibintu bifasha mu gutuma umubiri ugira uburebure bw’ibinyabuzima, lysozyme n’ibinyabuzima bitera imigera vyatumye uburebure bw’ibinyabuzima n’uburebure bw’ibinyabuzima (V/C) bitera imbere cane (P < 0.05); ibiva mu bimera, enzymes, ibintu bifasha mu gutuma umubiri ugira ubudahangarwa bw’umubiri (P < 0.05). AMP nziza, fagi, lysozyme, ibihimba bitobito, oligosaccharides, aside organiques, ibitegwa, ibiva mu bimera, probiotiques n’intungamubiri z’ibinyabuzima vyongeweko ku rugero rwa 0,100%, 0,150%, 0,012%, 0,010%, 0,070%,20,0. 0,040%, 0,180% na 0,100%, hakurikijwe uko vyari bimeze. Ugereranije n’imiti irwanya indwara, ikintu cose co kwongerako mu ngaburo nta ngaruka zikomeye cari gifise ku bijanye n’ukukura kw’ingurube, IgG n’index/rate y’ugucika intege (P > 0.05); AMPs n’ibihimba vy’umubiri vyiyongereye cane V/C (P < 0.05); n’ibiteguro vy’intungamubiri vyatumye urugero rw’amaraso rwongerekana cane (P < 0.05). Ikindi, hakoreshejwe uburyo bwo gucapura bufise uburemere bushingiye ku murongo kugira ngo hasuzumwe neza ingaruka rusangi z’ivyongera vyose ku ngaburo ku gukura no ku buzima bw’ingurube.
Iciyumviro
Ivyo twabonye vyerekana ko amapeptide arwanya imigera n’ibiva mu bimera bishobora gukoreshwa nk’ibisubirira imiti igabanya ubukana bw’indwara (ASs) ku ngurube zicutse n’ingurube ziriko zirakura. Amafagi, enzymes, ibiterwa, probiotiques, oligosaccharides, lysozyme n’ibindi bihimba bishobora gukoreshwa nk’ibihimba vy’umubiri bishobora gukoreshwa nk’ibihimba vy’umubiri bita AS vy’inyuma. nucleotides n’aside z’ibinyabuzima bishobora gufatwa nk’ivy’agaciro ka gatatu Ass. inyigisho zo muri kazoza zikwiye kurushiriza gusuzuma ingaruka z’ugusubirirana kw’ibifungurwa vy’inyongera bihuriweko.
